Polymers in Medicine

Polim. Med.
Scopus CiteScore: 3.5 (CiteScore Tracker 3.6)
Index Copernicus (ICV 2023) – 121.14
MEiN – 70
ISSN 0370-0747 (print)
ISSN 2451-2699 (online) 
Periodicity – biannual

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Polymers in Medicine

2023, vol. 53, nr 1, January-June, p. 81–89

doi: 10.17219/pim/165977

Publication type: review

Language: English

License: Creative Commons Attribution 3.0 Unported (CC BY 3.0)

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Choudhary A, Noman M, Bano U, Akhtar J, Shaikh Y, Shahar Yar M. Global uses of traditional herbs for hepatic diseases and other pharmacological actions: A comprehensive review. Polim Med. 2023;53(1):81–89. doi:10.17219/pim/165977

Global uses of traditional herbs for hepatic diseases and other pharmacological actions: A comprehensive review

Akram Choudhary1,A,D, Mohammad Noman1,B, Uzma Bano2,E, Jamal Akhtar3,E, Yahya Shaikh1,C, Mohammad Shahar Yar1,E,F

1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard University, New Delhi, India

2 School of Unani Medical Education and Research (SUMER), Jamia Hamdard University, New Delhi, India

3 Central Council for Research in Unani Medicine, Ministry of Ayurveda, Yoga & Naturopathy, Unani, Siddha, Sowa Rigpa, and Homeopathy (AYUSH), Government of India, New Delhi, India

Abstract

Hepatocellular carcinoma (HCC) is the 7th most common cancer and the 3rd leading cause of cancer-related death worldwide. It is resistant to the majority of chemotherapeutics and has a dismal prognosis. Hepatocellular carcinoma is a prevalent complication of chronic liver disease (CLD) in India. Primary liver cancer is the 6th most common cancer worldwide and the 4th most prevalent cause of cancer-related death. In 2018, it affected 841,000 people and caused 782,000 deaths around the world. Thus, research into the tumor cycle and its prevention through suitable herbal (Unani/Ayurvedic) medication is critical for reducing the impact of primary liver cancer. Treatment options for end-stage liver cancer are limited, necessitating costly liver transplantation, which is unavailable in most countries. Here, we present the results of a comprehensive literature survey to determine the benefits of using various herbs with liver protective and antioxidant properties. This information will be useful to researchers working on liver carcinoma and free radical scavenging, both of which are important in curbing potential carcinogens.

Key words

HCC, anti-oxidant, Bauhinia variegata, Picrorhiza kurroa, traditional Unani medicine

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