Polymers in Medicine
2013, vol. 43, nr 4, October-December, p. 231–233
Publication type: original article
Language: English
Mango Peel Pectin as a Carrier for Solid Dispersions
1 Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, India
Abstract
Objectives. The present study describes the evaluation of pectin as a carrier for solid dispersion.
Material and Methods. Pectin was extracted from mango peel. Solid dispersions were prepared by using pectin to enhance the dissolution rate of the drug. Aceclofenac was used as the model drug.
Results. Solid dispersion containing pectin had comparatively less release of the drug as compared to lactose for a particular time period.
Conclusion. The slower release may be due to the solubility of pectin in an aqueous fluid and it’s swelling capacity. With that in mind, it can be used as a carrier to prepare solid dispersions.
Key words
mango peel pectin, solid dispersion, dissolution, lactose
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