Polymers in Medicine

Polim. Med.
Scopus CiteScore: 3.5 (CiteScore Tracker 3.6)
Index Copernicus (ICV 2023) – 121.14
MEiN – 70
ISSN 0370-0747 (print)
ISSN 2451-2699 (online) 
Periodicity – biannual

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Polymers in Medicine

2013, vol. 43, nr 1, January-March, p. 45–48

Publication type: review article

Language: English

Rosin: A naturally derived excipient in drug delivery systems

Kalafonia: naturalnie uzyskiwana substancja pomocnicza w systemach dostarczania leku

Shobhit Kumar1,, Satish Kumar Gupta1,

1 Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Delhi-Roorkee Highway, NH-58, Baghpat Crossing, Meerut-250005, U.P. India

Abstract

Natural polymers are primarily attractive because they are biodegradable, inexpensive, and readily available. The most important benefit of natural polymers is that they are capable for chemical modifications. One such biopolymer, rosin, and its derivatives have been pharmaceutically evaluated as microencapsulating materials, film forming agent and as binding agent in formulation of tablets. They are also employed in formulation of chewing gum bases and cosmetics. This review article provides an overview of pharmaceutical use of rosin and its derivatives as excipient in dosage forms as well as novel drug delivery systems.

Streszczenie

Naturalne polimery ulegają biodegradacji, są tanie i łatwo dostępne. Najistotniejszą korzyścią zastosowania naturalnych polimerów jest ich zdolność do poddawania się chemicznym modyfikacjom. Jednym z takich biopolimerów jest kalafonia oraz jej pochodne, które były oceniane farmaceutycznie jako materiały w mikrokapsułkowaniu, środki tworzące błonę oraz środki wiążące w preparatach tabletkowych. Są one również stosowane w formowaniu gumy do żucia i kosmetyków. W artykule przedstawiono przegląd farmaceutycznego wykorzystania kalafonii i jej pochodnych jako substancji pomocniczych w formach dawkowania oraz systemach dostarczania leków.

Key words

rosin, biodegradable, drug delivery, controlled release, sustained release, film forming agent

Słowa kluczowe

kalafonia, podaż leku, kontrolowane uwalnianie, przedłużone uwalnianie, środek tworzący błonę

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