Polymers in Medicine

Polim. Med.
Scopus CiteScore: 3.5 (CiteScore Tracker 3.6)
Index Copernicus (ICV 2023) – 121.14
MEiN – 70
ISSN 0370-0747 (print)
ISSN 2451-2699 (online) 
Periodicity – biannual

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Polymers in Medicine

2012, vol. 42, nr 3, July-December, p. 191–197

Publication type: review article

Language: English

Natural polymers, gums and mucilages as excipients in drug delivery

Naturalne polimery, żywice i kleje roślinne jako substancje pomocnicze w podawaniu leku

Shobhit Kumar1,, Satish Kumar Gupta1,

1 Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Delhi-Roorkee Highway, NH-58, Baghpat Crossing, Meerut-250005, U.P. India

Abstract

Use of natural polymers, gums and mucilages in drug delivery systems has been weighed down by the synthetic materials. Natural based excipients offered advantages such as non-toxicity, less cost and abundantly availablity. Aqueous solubility of natural excipients plays an important role in their selection for designing immediate, controlled or sustained release formulations. This review article provide an overview of natural gum, polymers and mucilages as excipients in dosage forms as well as novel drug delivery systems.

Streszczenie

Wykorzystanie naturalnych polimerów, żywic i klejów roślinnych w systemach podawania leków, zostało zdominowane przez użycie materiałów syntetycznych. Substancje pomocnicze pochodzenia naturalnego oferują takie zalety, jak nietoksyczność, mniejsze koszty i szeroką dostępność. Rozpuszczalność w wodzie naturalnych substancji pomocniczych odgrywa ważną rolę w ich wyborze w projektowaniu preparatów o natychmiastowym, kontrolowanym i przedłużonym uwalnianianiu. Artykuł ten dostarcza informacji na temat naturalnych żywic, polimerów i klejów roślinnych, jako substancji pomocniczych w postaciach leku oraz w nowych systemach podawania leku.

Key words

natural polymers, excipients, drug delivery, gums, mucilages, controlled release, sustained release

Słowa kluczowe

naturalne polimery, substancje pomocnicze, podawanie leku, żywice, kleje roślinne, kontrolowane uwalnianie, przedłużone uwalnianie

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