Polymers in Medicine

Polim. Med.
Scopus CiteScore: 3.5 (CiteScore Tracker 3.6)
Index Copernicus (ICV 2023) – 121.14
MEiN – 70
ISSN 0370-0747 (print)
ISSN 2451-2699 (online) 
Periodicity – biannual

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Polymers in Medicine

2012, vol. 42, nr 2, April-June, p. 109–114

Publication type: review article

Language: Polish

Materiały zastępcze skóry – teraźniejszość i przyszłość

Skin substitutes – the present and the future

Jerzy Gosk1,

1 Katedra Chirurgii Urazowej, Klinika Chirurgii Urazowej i Chirurgii Ręki, Akademia Medyczna we Wrocławiu

Streszczenie

Ubytki skóry pełnej grubości są najczęściej wskazaniem do wykonania autologicznego przeszczepu skóry. W rozległych jej uszkodzeniach czasami konieczne jest zastosowanie materiałów zastępczych skóry. W pracy przedstawiono podział materiałów zastępczych skóry (stałe, czasowe, biologiczne, syntetyczne), oraz zaprezentowano różne rodzaje substytutów dopuszczonych do masowej produkcji (substytuty naskórka, substytuty skóry właściwej, substytuty złożone skórno-naskórkowe). Ponadto zaprezentowano przypadki zastosowań klinicznych materiałów zastępczych skóry oraz wyniki uzyskane przez wielu autorów po ich zastosowaniu. Wskazano również na istniejące nadal ograniczenia w możliwościach odtworzenia wszystkich funkcji skóry, oraz przedstawiono kierunki dalszego rozwoju badań.

Abstract

Full-thickness skin deficits are indications to autologic skin graft. In extensive skin injuries an employment of skin substitutes is sometimes necessary. In this study we presented the classification of skin substitutes (permanent, temporary, biological, synthetic). The different kinds of skin substitutes approved to commercial production were described (epidermal substitutes, dermal substitutes, composite dermo-epidermal substitutes). The possibilities of clinical applications of skin equivalents and results obtained by many authors after employment of artificial skin were also presented. Still existing limitations in possibilities of recovery of all skin functions were emphasized and the directions of future development of the studies were presented.

Słowa kluczowe

skóra ludzka, materiały zastępcze skóry, syntetyczne substytuty skóry

Key words

human skin, living skin replacements, synthetic skin substitutes

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